Regulatory Network in Protein Phosphorylation
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Kinase: DMPK1 dystrophia myotonica-protein kinase

Group: AGC      Family: DMPK      Subfamily: GEK

Description: dystrophia myotonica-protein kinase

Gene Symbol: DMPK

Synonyms: DM, DM1, DM1PK, DMK

UniprotKB/SwissProt: DMPK_HUMAN (Q09013)

Function: Critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity. Phosphorylates phospholamban.

Subcellular Localization:

Protein Domain:
PDB:1WT6

The substrate proteins of kinase DMPK1

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1PPP1R12AMYPT1_HUMANProtein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Proteinphosphatase myosin-binding subunit). 1Show