|Group: AGC Family: DMPK Subfamily: GEK|
Description: CDC42 binding protein kinase beta (DMPK-like)
Gene Symbol: CDC42BPB
Synonyms: KIAA1124, MRCKB
UniprotKB/SwissProt: MRCKB_HUMAN (Q9Y5S2)
Function: May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity).
Subcellular Localization: Cytoplasm (By similarity). Note=Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent (By similarity).