Regulatory Network in Protein Phosphorylation
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Kinase: PKACa protein kinase, cAMP-dependent, catalytic, alpha

Group: AGC      Family: PKA      

Description: protein kinase, cAMP-dependent, catalytic, alpha

Gene Symbol: PRKACA

Synonyms: MGC102831, MGC48865, PKACA

UniprotKB/SwissProt: KAPCA_HUMAN (P17612)

Function: Phosphorylates a large number of substrates in the cytoplasm and the nucleus.

Subcellular Localization: Cytoplasm (By similarity). Nucleus (By similarity). Note=Translocates into the nucleus (monomeric catalytic subunit) (By similarity). The inactive holoenzyme is found in the cytoplasm (By similarity).

Protein Domain:
PDB:2GU8

The substrate proteins of kinase PKACa

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1YWHAZ1433Z_HUMAN14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1)(KCIP-1). 1Show
2ABCA1ABCA1_HUMANATP-binding cassette sub-family A member 1 (ATP-binding cassettetransporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol effluxregulatory protein). 2Show
3ACCN2ACCN2_HUMANAmiloride-sensitive cation channel 2, neuronal (Acid-sensing ionchannel 1) (ASIC1) (Brain sodium channel 2) (BNaC2). 1Show
4ACLYACLY_HUMANATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase)(Citrate cleavage enzyme). 2Show
5ADD1ADDA_HUMANAlpha-adducin (Erythrocyte adducin subunit alpha). 2Show
6ADD2ADDB_HUMANBeta-adducin (Erythrocyte adducin subunit beta). 2Show
7APCAPC_HUMANAdenomatous polyposis coli protein (Protein APC). 1Show
8ADRBK1ARBK1_HUMANBeta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G-protein coupled receptor kinase 2). 1Show
9ATP2B1AT2B1_HUMANPlasma membrane calcium-transporting ATPase 1 (EC 3.6.3.8) (PMCA1)(Plasma membrane calcium pump isoform 1) (Plasma membrane calciumATPase isoform 1). 1Show
10ATF1ATF1_HUMANCyclic AMP-dependent transcription factor ATF-1 (Activatingtranscription factor 1) (TREB36 protein). 1Show
11BADBAD_HUMANBcl2 antagonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-XL/Bcl-2-associated death promoter) (Bcl-2-like 8 protein). 2Show
12BRAFBRAF1_HUMANB-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1)(p94) (v-Raf murine sarcoma viral oncogene homolog B1). 1Show
13CIITAC2TA_HUMANMHC class II transactivator (CIITA). 2Show
14CACNA1CCAC1C_HUMANVoltage-dependent L-type calcium channel subunit alpha-1C (Voltage-gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type,alpha-1 polypeptide, isoform 1, cardiac muscle). 3Show
15CACNB2CACB2_HUMANVoltage-dependent L-type calcium channel subunit beta-2 (CAB2)(Calcium channel voltage-dependent subunit beta 2) (Lambert-Eatonmyasthenic syndrome antigen B) (MYSB). 6Show
16CACNG2CCG2_HUMANVoltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit). 1Show
17CCND1CCND1_HUMANG1/S-specific cyclin-D1 (PRAD1 oncogene) (BCL-1 oncogene). 3Show
18CETN1CETN1_HUMANCentrin-1 (Caltractin isoform 2). 1Show
19CFTRCFTR_HUMANCystic fibrosis transmembrane conductance regulator (CFTR) (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7). 5Show
20CLDN3CLD3_HUMANClaudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-receptor 2) (CPE-R 2) (Ventral prostate.1 protein homolog) (HRVP1). 1Show
21CREMCREM_HUMANcAMP-responsive element modulator (Inducible cAMP early repressor)(ICER). 1Show
22CSKCSK_HUMANTyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL). 1Show
23CUL5CUL5_HUMANCullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor)(VACM-1). 1Show
24GJB1CXB1_HUMANGap junction beta-1 protein (Connexin-32) (Cx32) (GAP junction 28 kDaliver protein). 1Show
25EPB49DEMA_HUMANDematin (Erythrocyte membrane protein band 4.9). 1Show
26DSPDESP_HUMANDesmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen). 1Show
27DNAJC5DNJC5_HUMANDnaJ homolog subfamily C member 5 (Cysteine string protein) (CSP). 1Show
28EEF2KEF2K_HUMANElongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K)(Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase). 2Show
29ETV1ETV1_HUMANETS translocation variant 1 (Protein ER81). 3Show
30PFKFB2F262_HUMAN6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru-2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase(EC 3.1.3.46)]. 1Show
31FOSFOS_HUMANProto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switchregulatory protein 7). 1Show
32GFAPGFAP_HUMANGlial fibrillary acidic protein (GFAP). 3Show
33GMFBGMFB_HUMANGlia maturation factor beta (GMF-beta). 2Show
34GNA13GNA13_HUMANGuanine nucleotide-binding protein alpha-13 subunit (G alpha-13). 1Show
35GP1BBGP1BB_HUMANPlatelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB)(GPIb-beta) (Antigen CD42b-beta) (CD42c antigen). 1Show
36GRIA1GRIA1_HUMANGlutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamatereceptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1). 1Show
37GRIA4GRIA4_HUMANGlutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamatereceptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4). 1Show
38GSK3AGSK3A_HUMANGlycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha). 1Show
39GSK3BGSK3B_HUMANGlycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta). 1Show
40GSBSGSUB_HUMANG-substrate. 2Show
41SLC2A2GTR2_HUMANSolute carrier family 2, facilitated glucose transporter member 2(Glucose transporter type 2, liver) (GLUT-2). 3Show
42GYS1GYS1_HUMANGlycogen [starch] synthase, muscle (EC 2.4.1.11). 2Show
43HAND1HAND1_HUMANHeart- and neural crest derivatives-expressed protein 1(Extraembryonic tissues, heart, autonomic nervous system and neuralcrest derivatives-expressed protein 1) (eHAND). 3Show
44HDAC8HDAC8_HUMANHistone deacetylase 8 (HD8). 1Show
45HMGN1HMGN1_HUMANNon-histone chromosomal protein HMG-14 (High-mobility groupnucleosome-binding domain-containing protein 1). 3Show
46HMGN2HMGN2_HUMANNon-histone chromosomal protein HMG-17 (High-mobility groupnucleosome-binding domain-containing protein 2). 2Show
47HNRPDHNRPD_HUMANHeterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich elementRNA-binding protein 1). 1Show
48ITPKAIP3KA_HUMANInositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A). 1Show
49ITGA4ITA4_HUMANIntegrin alpha-4 precursor (Integrin alpha-IV) (VLA-4) (CD49dantigen). 1Show
50ITPR1ITPR1_HUMANInositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform1) (InsP3R1) (IP3R). 2Show
51KCNH2KCNH2_HUMANPotassium voltage-gated channel subfamily H member 2 (Voltage-gatedpotassium channel subunit Kv11.1) (Ether-a-go-go-related genepotassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1)(Eag-related protein 1) (eag homolog). 2Show
52KLF1KLF1_HUMANKrueppel-like factor 1 (Erythroid krueppel-like transcription factor)(EKLF) (Erythroid transcription factor). 1Show
53PHKA1KPB1_HUMANPhosphorylase b kinase regulatory subunit alpha, skeletal muscleisoform (Phosphorylase kinase alpha M subunit). 1Show
54LCKLCK_HUMANProto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK)(Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase). 1Show
55LIPELIPS_HUMANHormone-sensitive lipase (EC 3.1.1.79) (HSL). 4Show
56LRP1LRP1_HUMANProlow-density lipoprotein receptor-related protein 1 precursor (LRP)(Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor)(APOER) (CD91 antigen) [Contains: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoproteinreceptor-related protein 1 515 kDa subunit (LRP-515); Low-densitylipoprotein receptor-related protein 1 intracellular domain (LRPICD)]. 1Show
57MAP3K3M3K3_HUMANMitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25)(MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3). 3Show
58MAP2MAP2_HUMANMicrotubule-associated protein 2 (MAP 2) (MAP-2). 1Show
59MBPMBP_HUMANMyelin basic protein (MBP) (Myelin A1 protein) (Myelin membraneencephalitogenic protein). 6Show
60MC4RMC4R_HUMANMelanocortin receptor 4 (MC4-R). 3Show
61MIPMIP_HUMANLens fiber major intrinsic protein (Aquaporin-0) (MIP26) (MP26). 2Show
62PPP1R9BNEB2_HUMANNeurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1regulatory subunit 9B). 2Show
63NFKB1NFKB1_HUMANNuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) [Contains: Nuclear factor NF-kappa-B p50 subunit]. 1Show
64NOLC1NOLC1_HUMANNucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDanucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-bodyphosphoprotein 1). 2Show
65NOS1NOS1_HUMANNitric oxide synthase, brain (EC 1.14.13.39) (NOS type I) (NeuronalNOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS). 1Show
66PCTK1PCTK1_HUMANSerine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE-motif protein kinase 1). 4Show
67PDE3BPDE3B_HUMANcGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (CyclicGMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1). 1Show
68PDE4BPDE4B_HUMANcAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.17) (DPDE4)(PDE32). 1Show
69PDE4DPDE4D_HUMANcAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3)(PDE43). 1Show
70PDCPHOS_HUMANPhosducin (PHD) (33 kDa phototransducing protein) (MEKA protein). 1Show
71LCP1PLSL_HUMANPlastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1)(LC64P). 1Show
72PPP1R8PP1R8_HUMANNuclear inhibitor of protein phosphatase 1 (NIPP-1) (Proteinphosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator ofRNA decay (EC 3.1.4.-) (ARD-1)]. 2Show
73PLNPPLA_HUMANCardiac phospholamban (PLB). 1Show
74PPP1R1BPPR1B_HUMANProtein phosphatase 1 regulatory subunit 1B (Dopamine- and cAMP-regulated neuronal phosphoprotein) (DARPP-32). 1Show
75PSEN1PSN1_HUMANPresenilin-1 (EC 3.4.23.-) (PS-1) (Protein S182) [Contains:Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12(PS1-CTF12)]. 1Show
76PTBP1PTBP1_HUMANPolypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclearribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding protein PPTB-1). 1Show
77PTPN12PTN12_HUMANTyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48)(Protein-tyrosine phosphatase G1) (PTPG1) (PTP-PEST). 2Show
78PTPN7PTN7_HUMANTyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48)(Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosinephosphatase) (HEPTP). 1Show
79PTPRRPTPRR_HUMANReceptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48)(Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase). 1Show
80CADPYR1_HUMANCAD protein [Includes: Glutamine-dependent carbamoyl-phosphatesynthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2);Dihydroorotase (EC 3.5.2.3)]. 2Show
81RRADRAD_HUMANGTP-binding protein RAD (RAS associated with diabetes) (RAD1). 2Show
82RAF1RAF1_HUMANRAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf-1) (C-RAF) (cRaf). 4Show
83RAP1ARAP1A_HUMANRas-related protein Rap-1A precursor (GTP-binding protein smg-p21A)(Ras-related protein Krev-1) (C21KG) (G-22K). 1Show
84RAP1BRAP1B_HUMANRas-related protein Rap-1b precursor (GTP-binding protein smg p21B). 1Show
85RASGRF1RGRF1_HUMANRas-specific guanine nucleotide-releasing factor 1 (Ras-GRF1) (Guaninenucleotide-releasing protein) (Ras-specific nucleotide exchange factorCDC25) (Guanine nucleotide-releasing factor 1). 1Show
86RGS10RGS10_HUMANRegulator of G-protein signaling 10 (RGS10). 1Show
87RGS14RGS14_HUMANRegulator of G-protein signaling 14 (RGS14). 2Show
88RHOARHOA_HUMANTransforming protein RhoA precursor (H12). 1Show
89RAP1GAPRPGP1_HUMANRap1 GTPase-activating protein 1 (Rap1GAP1) (Rap1GAP). 2Show
90RYR1RYR1_HUMANRyanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1)(RYR-1) (Skeletal muscle calcium release channel). 1Show
91RYR2RYR2_HUMANRyanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2)(RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel)(hRYR-2). 1Show
92SNAPAPS25BP_HUMANSNARE-associated protein Snapin (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein). 1Show
93SLC4A4S4A4_HUMANElectrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonatecotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4member 4) (kNBC1). 1Show
94AANATSNAT_HUMANSerotonin N-acetyltransferase (EC 2.3.1.87) (Aralkylamine N-acetyltransferase) (AA-NAT) (Serotonin acetylase). 2Show
95SNAP25SNP25_HUMANSynaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated25 kDa protein) (Super protein) (SUP). 1Show
96SPTBN1SPTB2_HUMANSpectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1)(Beta-II spectrin) (Fodrin beta chain). 1Show
97SRCSRC_HUMANProto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src). 1Show
98STK11STK11_HUMANSerine/threonine-protein kinase 11 (EC 2.7.11.1) (Serine/threonine-protein kinase LKB1) (Renal carcinoma antigen NY-REN-19). 1Show
99AURKASTK6_HUMANSerine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)(Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase). 1Show
100STMN1STMN1_HUMANStathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)(Leukemia-associated phosphoprotein p18) (pp17) (Prosolin)(Metablastin) (Protein Pr22). 3Show
101STMN2STMN2_HUMANStathmin-2 (Protein SCG10) (Superior cervical ganglion-10 protein). 2Show
102SISUIS_HUMANSucrase-isomaltase, intestinal [Contains: Sucrase (EC 3.2.1.48);Isomaltase (EC 3.2.1.10)]. 1Show
103SYN1SYN1_HUMANSynapsin-1 (Synapsin I) (Brain protein 4.1). 1Show
104SYN2SYN2_HUMANSynapsin-2 (Synapsin II). 1Show
105MAPTTAU_HUMANMicrotubule-associated protein tau (Neurofibrillary tangle protein)(Paired helical filament-tau) (PHF-tau). 12Show
106RELATF65_HUMANTranscription factor p65 (Nuclear factor NF-kappa-B p65 subunit). 1Show
107THOP1THOP1_HUMANThimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78). 1Show
108TPH1TPH1_HUMANTryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase1). 1Show
109THTY3H_HUMANTyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH). 1Show
110VASPVASP_HUMANVasodilator-stimulated phosphoprotein (VASP). 3Show
111VIMVIME_HUMANVimentin. 4Show
112VTNVTNC_HUMANVitronectin precursor (Serum-spreading factor) (S-protein) (V75)[Contains: Vitronectin V65 subunit; Vitronectin V10 subunit;Somatomedin-B]. 1Show
113WT1WT1_HUMANWilms tumor protein (WT33). 2Show



The substrate proteins of kinase family PKA

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1YWHAZ1433Z_HUMAN14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1)(KCIP-1). 3Show
2HLA-A1A01_HUMANHLA class I histocompatibility antigen, A-1 alpha chain precursor (MHCclass I antigen A*1). 3Show
3ABCA1ABCA1_HUMANATP-binding cassette sub-family A member 1 (ATP-binding cassettetransporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol effluxregulatory protein). 6Show
4ACACAACACA_HUMANAcetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotincarboxylase (EC 6.3.4.14)]. 7Show
5ACACBACACB_HUMANAcetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotincarboxylase (EC 6.3.4.14)]. 1Show
6ACCN2ACCN2_HUMANAmiloride-sensitive cation channel 2, neuronal (Acid-sensing ionchannel 1) (ASIC1) (Brain sodium channel 2) (BNaC2). 3Show
7ACLYACLY_HUMANATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase)(Citrate cleavage enzyme). 3Show
8ADRA1AADA1A_HUMANAlpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A-adrenoreceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergicreceptor 1c). 1Show
9ADD1ADDA_HUMANAlpha-adducin (Erythrocyte adducin subunit alpha). 11Show
10ADD2ADDB_HUMANBeta-adducin (Erythrocyte adducin subunit beta). 7Show
11ADRB1ADRB1_HUMANBeta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). 2Show
12ADRB2ADRB2_HUMANBeta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). 7Show
13AKAP13AKP13_HUMANA-kinase anchor protein 13 (AKAP 13) (Protein kinase A-anchoringprotein 13) (Breast cancer nuclear receptor-binding auxiliary protein)(Human thyroid-anchoring protein 31) (Guanine nucleotide exchangefactor Lbc) (AKAP-Lbc) (LBC oncogene) (P47) (Lymphoid blast crisisoncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor). 2Show
14NPR1ANPRA_HUMANAtrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A)(Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptideA-type receptor). 1Show
15ANXA1ANXA1_HUMANAnnexin A1 (Annexin-1) (Annexin I) (Lipocortin I) (Calpactin II)(Chromobindin-9) (p35) (Phospholipase A2 inhibitory protein). 1Show
16TFAP2AAP2A_HUMANTranscription factor AP-2 alpha (AP2-alpha) (Activating enhancer-binding protein 2 alpha) (AP-2 transcription factor) (Activatorprotein 2) (AP-2). 1Show
17TFAP2BAP2B_HUMANTranscription factor AP-2 beta (AP2-beta) (Activating enhancer-bindingprotein 2 beta). 1Show
18TFAP2CAP2C_HUMANTranscription factor AP-2 gamma (AP2-gamma) (Activating enhancer-binding protein 2 gamma) (Transcription factor ERF-1). 1Show
19TFAP2DAP2D_HUMANTranscription factor AP-2 delta (AP2-delta) (Activating enhancer-binding protein 2 delta) (Transcription factor AP-2 beta-like 1). 1Show
20TFAP2EAP2E_HUMANTranscription factor AP-2 epsilon (AP2-epsilon) (Activating enhancer-binding protein 2 epsilon). 1Show
21APCAPC_HUMANAdenomatous polyposis coli protein (Protein APC). 2Show
22AQP2AQP2_HUMANAquaporin-2 (AQP-2) (Aquaporin-CD) (AQP-CD) (Water channel protein forrenal collecting duct) (ADH water channel) (Collecting duct waterchannel protein) (WCH-CD). 2Show
23ADRBK1ARBK1_HUMANBeta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G-protein coupled receptor kinase 2). 2Show
24ARPP19ARP19_HUMANcAMP-regulated phosphoprotein 19 (ARPP-19). 1Show
25ATP12AAT12A_HUMANPotassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Protonpump) (Non-gastric H(+)/K(+) ATPase subunit alpha). 1Show
26ATP1A1AT1A1_HUMANSodium/potassium-transporting ATPase subunit alpha-1 precursor(EC 3.6.3.9) (Sodium pump subunit alpha-1) (Na(+)/K(+) ATPase alpha-1subunit). 1Show
27ATP1A2AT1A2_HUMANSodium/potassium-transporting ATPase subunit alpha-2 precursor(EC 3.6.3.9) (Sodium pump subunit alpha-2) (Na(+)/K(+) ATPase alpha-2subunit). 1Show
28ATP1A3AT1A3_HUMANSodium/potassium-transporting ATPase subunit alpha-3 (EC 3.6.3.9)(Sodium pump subunit alpha-3) (Na(+)/K(+) ATPase alpha-3 subunit)(Na(+)/K(+) ATPase alpha(III) subunit). 1Show
29ATP1A4AT1A4_HUMANSodium/potassium-transporting ATPase subunit alpha-4 (EC 3.6.3.9)(Sodium pump subunit alpha-4) (Na(+)/K(+) ATPase alpha-4 subunit). 1Show
30ATP2B1AT2B1_HUMANPlasma membrane calcium-transporting ATPase 1 (EC 3.6.3.8) (PMCA1)(Plasma membrane calcium pump isoform 1) (Plasma membrane calciumATPase isoform 1). 3Show
31ATP2B2AT2B2_HUMANPlasma membrane calcium-transporting ATPase 2 (EC 3.6.3.8) (PMCA2)(Plasma membrane calcium pump isoform 2) (Plasma membrane calciumATPase isoform 2). 1Show
32ATF1ATF1_HUMANCyclic AMP-dependent transcription factor ATF-1 (Activatingtranscription factor 1) (TREB36 protein). 1Show
33ATF2ATF2_HUMANCyclic AMP-dependent transcription factor ATF-2 (Activatingtranscription factor 2) (cAMP response element-binding protein CRE-BP1) (HB16). 1Show
34ATP4AATP4A_HUMANPotassium-transporting ATPase alpha chain 1 (EC 3.6.3.10) (Protonpump) (Gastric H(+)/K(+) ATPase subunit alpha). 1Show
35BADBAD_HUMANBcl2 antagonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-XL/Bcl-2-associated death promoter) (Bcl-2-like 8 protein). 6Show
36BAG2BAG2_HUMANBAG family molecular chaperone regulator 2 (Bcl-2-associatedathanogene 2) (BAG-2). 2Show
37BFSP1BFSP1_HUMANFilensin (Beaded filament structural protein 1) (Lens fiber cellbeaded-filament structural protein CP 115) (CP115) (Lens intermediatefilament-like heavy) (LIFL-H). 1Show
38BRAFBRAF1_HUMANB-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1)(p94) (v-Raf murine sarcoma viral oncogene homolog B1). 2Show
39CIITAC2TA_HUMANMHC class II transactivator (CIITA). 4Show
40CACNA1ACAC1A_HUMANVoltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage-gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type,alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI). 1Show
41CACNA1BCAC1B_HUMANVoltage-dependent N-type calcium channel subunit alpha-1B (Voltage-gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type,alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII). 1Show
42CACNA1CCAC1C_HUMANVoltage-dependent L-type calcium channel subunit alpha-1C (Voltage-gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type,alpha-1 polypeptide, isoform 1, cardiac muscle). 6Show
43CACNA1DCAC1D_HUMANVoltage-dependent L-type calcium channel subunit alpha-1D (Voltage-gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type,alpha-1 polypeptide, isoform 2). 1Show
44CACNA1ECAC1E_HUMANVoltage-dependent R-type calcium channel subunit alpha-1E (Voltage-gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type,alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII). 1Show
45CACNA1FCAC1F_HUMANVoltage-dependent L-type calcium channel subunit alpha-1F (Voltage-gated calcium channel subunit alpha Cav1.4). 1Show
46CACNA1SCAC1S_HUMANVoltage-dependent L-type calcium channel subunit alpha-1S (Voltage-gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type,alpha-1 polypeptide, isoform 3, skeletal muscle). 2Show
47CACNB2CACB2_HUMANVoltage-dependent L-type calcium channel subunit beta-2 (CAB2)(Calcium channel voltage-dependent subunit beta 2) (Lambert-Eatonmyasthenic syndrome antigen B) (MYSB). 10Show
48CAPN2CAN2_HUMANCalpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 largesubunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2). 2Show
49CAPSCAYP1_HUMANCalcyphosin (Calcyphosine). 1Show
50CACNG2CCG2_HUMANVoltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit). 1Show
51CCND1CCND1_HUMANG1/S-specific cyclin-D1 (PRAD1 oncogene) (BCL-1 oncogene). 6Show
52CDKN1ACDN1A_HUMANCyclin-dependent kinase inhibitor 1 (p21) (CDK-interacting protein 1)(Melanoma differentiation-associated protein 6) (MDA-6). 1Show
53CEBPBCEBPB_HUMANCCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear factor NF-IL6) (Transcription factor 5). 1Show
54CETN1CETN1_HUMANCentrin-1 (Caltractin isoform 2). 2Show
55CETN2CETN2_HUMANCentrin-2 (Caltractin isoform 1). 1Show
56CFTRCFTR_HUMANCystic fibrosis transmembrane conductance regulator (CFTR) (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7). 20Show
57CGBCGHB_HUMANChoriogonadotropin subunit beta precursor (CG-beta) (Chorionicgonadotrophin chain beta). 3Show
58CLDN3CLD3_HUMANClaudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-receptor 2) (CPE-R 2) (Ventral prostate.1 protein homolog) (HRVP1). 1Show
59CYP2B6CP2B6_HUMANCytochrome P450 2B6 (EC 1.14.14.1) (CYPIIB6) (P450 IIB1). 1Show
60RCSD1CPZIP_HUMANCapz-interacting protein (Protein kinase substrate CapZIP) (RCSDdomain-containing protein 1). 2Show
61CREB1CREB1_HUMANcAMP response element-binding protein (CREB). 2Show
62CREMCREM_HUMANcAMP-responsive element modulator (Inducible cAMP early repressor)(ICER). 1Show
63CSKCSK_HUMANTyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL). 1Show
64CUL5CUL5_HUMANCullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor)(VACM-1). 2Show
65GJB1CXB1_HUMANGap junction beta-1 protein (Connexin-32) (Cx32) (GAP junction 28 kDaliver protein). 2Show
66EPB49DEMA_HUMANDematin (Erythrocyte membrane protein band 4.9). 3Show
67DSPDESP_HUMANDesmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen). 3Show
68DNAJC5DNJC5_HUMANDnaJ homolog subfamily C member 5 (Cysteine string protein) (CSP). 1Show
69EEF2KEF2K_HUMANElongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K)(Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase). 12Show
70ENAHENAH_HUMANProtein enabled homolog. 1Show
71EPB42EPB42_HUMANErythrocyte membrane protein band 4.2 (Erythrocyte protein 4.2)(P4.2). 2Show
72ESR1ESR1_HUMANEstrogen receptor (ER) (Estradiol receptor) (ER-alpha) (Nuclearreceptor subfamily 3 group A member 1). 2Show
73ETV1ETV1_HUMANETS translocation variant 1 (Protein ER81). 5Show
74ETV5ETV5_HUMANETS translocation variant 5 (Ets-related protein ERM). 1Show
75PFKFB1F261_HUMAN6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (6PF-2-K/Fru-2,6-P2ASE liver isozyme) [Includes: 6-phosphofructo-2-kinase(EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]. 1Show
76PFKFB2F262_HUMAN6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru-2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase(EC 3.1.3.46)]. 4Show
77PFKFB3F263_HUMAN6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru-2,6-P2ASE brain/placenta-type isozyme) (iPFK-2) (Renal carcinomaantigen NY-REN-56) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105);Fructose-2,6-bisphosphatase (EC 3.1.3.46)]. 1Show
78FGF2FGF2_HUMANHeparin-binding growth factor 2 precursor (HBGF-2) (Basic fibroblastgrowth factor) (BFGF) (Prostatropin). 1Show
79FGAFIBA_HUMANFibrinogen alpha chain precursor [Contains: Fibrinopeptide A]. 1Show
80FOSFOS_HUMANProto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switchregulatory protein 7). 2Show
81GABRB1GBRB1_HUMANGamma-aminobutyric acid receptor subunit beta-1 precursor (GABA(A)receptor subunit beta-1). 1Show
82GFAPGFAP_HUMANGlial fibrillary acidic protein (GFAP). 3Show
83GFPT1GFPT1_HUMANGlucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1(EC 2.6.1.16) (Glutamine:fructose 6 phosphate amidotransferase 1)(Hexosephosphate aminotransferase 1) (D-fructose-6-phosphateamidotransferase 1) (GFAT 1) (GFAT1). 2Show
84GFPT2GFPT2_HUMANGlucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2(EC 2.6.1.16) (Glutamine:fructose 6 phosphate amidotransferase 2)(Hexosephosphate aminotransferase 2) (D-fructose-6-phosphateamidotransferase 2) (GFAT 2) (GFAT2). 1Show
85GMFBGMFB_HUMANGlia maturation factor beta (GMF-beta). 4Show
86GNA13GNA13_HUMANGuanine nucleotide-binding protein alpha-13 subunit (G alpha-13). 3Show
87GP1BBGP1BB_HUMANPlatelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB)(GPIb-beta) (Antigen CD42b-beta) (CD42c antigen). 3Show
88GPSM2GPSM2_HUMANG-protein-signaling modulator 2 (Mosaic protein LGN). 1Show
89GRIA1GRIA1_HUMANGlutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamatereceptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1). 2Show
90GRIA4GRIA4_HUMANGlutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamatereceptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4). 2Show
91GRIK2GRIK2_HUMANGlutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4). 3Show
92GRK7GRK7_HUMANG protein-coupled receptor kinase 7 precursor (EC 2.7.11.16) (Gprotein-coupled receptor kinase GRK7). 2Show
93GSK3AGSK3A_HUMANGlycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha). 2Show
94GSK3BGSK3B_HUMANGlycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta). 2Show
95GSBSGSUB_HUMANG-substrate. 2Show
96SLC2A2GTR2_HUMANSolute carrier family 2, facilitated glucose transporter member 2(Glucose transporter type 2, liver) (GLUT-2). 6Show
97GYS1GYS1_HUMANGlycogen [starch] synthase, muscle (EC 2.4.1.11). 3Show
98GYS2GYS2_HUMANGlycogen [starch] synthase, liver (EC 2.4.1.11). 1Show
99HIST1H2BCH2B1C_HUMANHistone H2B type 1-C/E/F/G/I (H2B.a/g/h/k/l) (H2B.1 A) (H2B/a) (H2B/g)(H2B/h) (H2B/k) (H2B/l). 3Show
100HAND1HAND1_HUMANHeart- and neural crest derivatives-expressed protein 1(Extraembryonic tissues, heart, autonomic nervous system and neuralcrest derivatives-expressed protein 1) (eHAND). 6Show
101HDAC8HDAC8_HUMANHistone deacetylase 8 (HD8). 2Show
102HMGN1HMGN1_HUMANNon-histone chromosomal protein HMG-14 (High-mobility groupnucleosome-binding domain-containing protein 1). 5Show
103HMGN2HMGN2_HUMANNon-histone chromosomal protein HMG-17 (High-mobility groupnucleosome-binding domain-containing protein 2). 2Show
104HNF4AHNF4A_HUMANHepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factorHNF-4) (Nuclear receptor subfamily 2 group A member 1) (Transcriptionfactor 14). 1Show
105HNRPDHNRPD_HUMANHeterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich elementRNA-binding protein 1). 2Show
106HRH1HRH1_HUMANHistamine H1 receptor. 1Show
107HSF1HSF1_HUMANHeat shock factor protein 1 (HSF 1) (Heat shock transcription factor1) (HSTF 1). 1Show
108HSPB1HSPB1_HUMANHeat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)(Stress-responsive protein 27) (SRP27) (Estrogen-regulated 24 kDaprotein) (28 kDa heat shock protein). 9Show
109CSF2RBIL3RB_HUMANCytokine receptor common subunit beta precursor (GM-CSF/IL-3/IL-5receptor common beta-chain) (CD131 antigen) (CDw131). 1Show
110ITPKAIP3KA_HUMANInositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A). 1Show
111ITGA4ITA4_HUMANIntegrin alpha-4 precursor (Integrin alpha-IV) (VLA-4) (CD49dantigen). 2Show
112ITPR1ITPR1_HUMANInositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform1) (InsP3R1) (IP3R). 3Show
113PFKLK6PL_HUMAN6-phosphofructokinase, liver type (EC 2.7.1.11) (Phosphofructokinase1) (Phosphohexokinase) (Phosphofructo-1-kinase isozyme B) (PFK-B). 1Show
114PRKAR2AKAP2_HUMANcAMP-dependent protein kinase type II-alpha regulatory subunit. 2Show
115PRKAR2BKAP3_HUMANcAMP-dependent protein kinase type II-beta regulatory subunit. 1Show
116KCNA1KCNA1_HUMANPotassium voltage-gated channel subfamily A member 1 (Voltage-gatedpotassium channel subunit Kv1.1) (HUKI) (HBK1). 2Show
117KCNA2KCNA2_HUMANPotassium voltage-gated channel subfamily A member 2 (Voltage-gatedpotassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV). 1Show
118KCNA3KCNA3_HUMANPotassium voltage-gated channel subfamily A member 3 (Voltage-gatedpotassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3). 1Show
119KCNA4KCNA4_HUMANPotassium voltage-gated channel subfamily A member 4 (Voltage-gatedpotassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII). 2Show
120KCNA5KCNA5_HUMANPotassium voltage-gated channel subfamily A member 5 (Voltage-gatedpotassium channel subunit Kv1.5) (HK2) (HPCN1). 1Show
121KCNA6KCNA6_HUMANPotassium voltage-gated channel subfamily A member 6 (Voltage-gatedpotassium channel subunit Kv1.6) (HBK2). 1Show
122KCNH2KCNH2_HUMANPotassium voltage-gated channel subfamily H member 2 (Voltage-gatedpotassium channel subunit Kv11.1) (Ether-a-go-go-related genepotassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1)(Eag-related protein 1) (eag homolog). 4Show
123KCNQ2KCNQ2_HUMANPotassium voltage-gated channel subfamily KQT member 2 (Voltage-gatedpotassium channel subunit Kv7.2) (Neuroblastoma-specific potassiumchannel subunit alpha KvLQT2) (KQT-like 2). 1Show
124CAMKK1KKCC1_HUMANCalcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17)(Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinasekinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IVkinase). 1Show
125KLF1KLF1_HUMANKrueppel-like factor 1 (Erythroid krueppel-like transcription factor)(EKLF) (Erythroid transcription factor). 1Show
126PHKA1KPB1_HUMANPhosphorylase b kinase regulatory subunit alpha, skeletal muscleisoform (Phosphorylase kinase alpha M subunit). 2Show
127PHKBKPBB_HUMANPhosphorylase b kinase regulatory subunit beta (Phosphorylase kinasesubunit beta). 2Show
128PKLRKPYR_HUMANPyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type pyruvatekinase) (Red cell/liver pyruvate kinase) (Pyruvate kinase 1). 1Show
129LASP1LASP1_HUMANLIM and SH3 domain protein 1 (LASP-1) (MLN 50). 1Show
130LCKLCK_HUMANProto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK)(Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase). 1Show
131LIPELIPS_HUMANHormone-sensitive lipase (EC 3.1.1.79) (HSL). 7Show
132ALOX5LOX5_HUMANArachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO). 5Show
133LRP1LRP1_HUMANProlow-density lipoprotein receptor-related protein 1 precursor (LRP)(Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor)(APOER) (CD91 antigen) [Contains: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoproteinreceptor-related protein 1 515 kDa subunit (LRP-515); Low-densitylipoprotein receptor-related protein 1 intracellular domain (LRPICD)]. 3Show
134LSP1LSP1_HUMANLymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein)(Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein). 5Show
135MAP3K3M3K3_HUMANMitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25)(MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3). 5Show
136MAP2MAP2_HUMANMicrotubule-associated protein 2 (MAP 2) (MAP-2). 1Show
137MAPKAPK2MAPK2_HUMANMAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activatedprotein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2). 1Show
138MBPMBP_HUMANMyelin basic protein (MBP) (Myelin A1 protein) (Myelin membraneencephalitogenic protein). 6Show
139MC4RMC4R_HUMANMelanocortin receptor 4 (MC4-R). 6Show
140ABCB1MDR1_HUMANMultidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassettesub-family B member 1) (P-glycoprotein 1) (CD243 antigen). 2Show
141NF2MERL_HUMANMerlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2)(Schwannomin) (Schwannomerlin). 1Show
142MIPMIP_HUMANLens fiber major intrinsic protein (Aquaporin-0) (MIP26) (MP26). 4Show
143MSNMOES_HUMANMoesin (Membrane-organizing extension spike protein). 1Show
144CDC25BMPIP2_HUMANM-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificityphosphatase Cdc25B). 1Show
145MYLKMYLK_HUMANMyosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK)(Telokin) (Kinase-related protein) (KRP). 1Show
146MYOM1MYOM1_HUMANMyomesin-1 (Myomesin family member 1) (190 kDa titin-associatedprotein) (190 kDa connectin-associated protein). 1Show
147MYBPC3MYPC3_HUMANMyosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein,cardiac muscle isoform). 3Show
148NCF1NCF1_HUMANNeutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDaautosomal chronic granulomatous disease protein) (Nox organizer 2)(Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A). 4Show
149NCOA1NCOA1_HUMANNuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroidreceptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (Renalcarcinoma antigen NY-REN-52). 2Show
150PPP1R9ANEB1_HUMANNeurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-bindingprotein I) (Protein phosphatase 1 regulatory subunit 9A). 1Show
151PPP1R9BNEB2_HUMANNeurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1regulatory subunit 9B). 4Show
152NEDD4LNED4L_HUMANE3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2)(NEDD4.2). 2Show
153NFE2L1NF2L1_HUMANNuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1)(NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1)(Transcription factor 11) (Transcription factor HBZ17) (Transcriptionfactor LCR-F1) (Locus control region-factor 1). 1Show
154NFATC1NFAC1_HUMANNuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcriptioncomplex cytosolic component) (NF-ATc1) (NF-ATc) (NFATc). 3Show
155NFKB1NFKB1_HUMANNuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) [Contains: Nuclear factor NF-kappa-B p50 subunit]. 3Show
156NOLC1NOLC1_HUMANNucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDanucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-bodyphosphoprotein 1). 3Show
157NOS1NOS1_HUMANNitric oxide synthase, brain (EC 1.14.13.39) (NOS type I) (NeuronalNOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS). 2Show
158NOS2ANOS2A_HUMANNitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II)(Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP-NOS). 3Show
159NOS3NOS3_HUMANNitric oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS typeIII) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS). 1Show
160NOXA1NOXA1_HUMANNADPH oxidase activator 1 (NOX activator 1) (P67phox-like factor)(p51-nox) (NCF2-like protein) (Antigen NY-CO-31). 2Show
161NR4A1NR4A1_HUMANNuclear receptor subfamily 4 group A member 1 (Orphan nuclear receptorHMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59). 2Show
162TBXA2RO75228_HUMANTA2R_HUMAN, BETA ISOFORM (Thromboxane A2 receptor, isoform CRA_a). 1Show
163PLA2G4APA24A_HUMANCytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA)[Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)]. 1Show
164PAWRPAWR_HUMANPRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4protein) (Par-4). 1Show
165PCTK1PCTK1_HUMANSerine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22) (PCTAIRE-motif protein kinase 1). 8Show
166PDE3BPDE3B_HUMANcGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (CyclicGMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1). 2Show
167PDE4BPDE4B_HUMANcAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.17) (DPDE4)(PDE32). 2Show
168PDE4DPDE4D_HUMANcAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3)(PDE43). 1Show
169PDE5APDE5A_HUMANcGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE)(cGMP-binding cGMP-specific phosphodiesterase). 1Show
170PTGER4PE2R4_HUMANProstaglandin E2 receptor EP4 subtype (Prostanoid EP4 receptor) (PGEreceptor, EP4 subtype). 2Show
171SERPINF1PEDF_HUMANPigment epithelium-derived factor precursor (PEDF) (Serpin-F1) (EPC-1). 1Show
172PAHPH4H_HUMANPhenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4-monooxygenase). 2Show
173PDCPHOS_HUMANPhosducin (PHD) (33 kDa phototransducing protein) (MEKA protein). 2Show
174PIN1PIN1_HUMANPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8)(Rotamase Pin1) (PPIase Pin1). 1Show
175PLCB3PLCB3_HUMAN1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3(EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-beta-3) (PLC-beta-3). 1Show
176PLCG1PLCG1_HUMAN1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1(EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1)(Phospholipase C-gamma-1) (PLC-II) (PLC-148). 1Show
177PLCL1PLCL1_HUMANInactive phospholipase C-like protein 1 (PLC-L1) (Phospholipase C-deleted in lung carcinoma) (Phospholipase C-related but catalyticallyinactive protein) (PRIP). 2Show
178FXYD1PLM_HUMANPhospholemman precursor (FXYD domain-containing ion transportregulator 1). 3Show
179LCP1PLSL_HUMANPlastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1)(LC64P). 3Show
180POU2F1PO2F1_HUMANPOU domain, class 2, transcription factor 1 (Octamer-bindingtranscription factor 1) (Oct-1) (OTF-1) (NF-A1). 1Show
181PPP1R14APP14A_HUMANProtein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiatedinhibitory protein of PP1) (CPI-17). 1Show
182PPP1R14DPP14D_HUMANProtein phosphatase 1 regulatory subunit 14D (Gastrointestinal andbrain-specific PP1-inhibitory protein 1) (GBPI-1). 1Show
183PPP1R8PP1R8_HUMANNuclear inhibitor of protein phosphatase 1 (NIPP-1) (Proteinphosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator ofRNA decay (EC 3.1.4.-) (ARD-1)]. 4Show
184PPP1R10PP1RA_HUMANSerine/threonine-protein phosphatase 1 regulatory subunit 10(Phosphatase 1 nuclear targeting subunit) (MHC class I region proline-rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa)(p99). 2Show
185PLNPPLA_HUMANCardiac phospholamban (PLB). 3Show
186PPP1R1APPR1A_HUMANProtein phosphatase 1 regulatory subunit 1A (Protein phosphataseinhibitor 1) (IPP-1) (I-1). 1Show
187PPP1R1BPPR1B_HUMANProtein phosphatase 1 regulatory subunit 1B (Dopamine- and cAMP-regulated neuronal phosphoprotein) (DARPP-32). 2Show
188PPP1R3APPR3A_HUMANProtein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1glycogen-associated regulatory subunit) (Protein phosphatase type-1glycogen targeting subunit). 4Show
189PSEN1PSN1_HUMANPresenilin-1 (EC 3.4.23.-) (PS-1) (Protein S182) [Contains:Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12(PS1-CTF12)]. 3Show
190PTBP1PTBP1_HUMANPolypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclearribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding protein PPTB-1). 2Show
191PTPN12PTN12_HUMANTyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48)(Protein-tyrosine phosphatase G1) (PTPG1) (PTP-PEST). 4Show
192PTPN7PTN7_HUMANTyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48)(Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosinephosphatase) (HEPTP). 2Show
193PTPRRPTPRR_HUMANReceptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48)(Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase). 2Show
194CADPYR1_HUMANCAD protein [Includes: Glutamine-dependent carbamoyl-phosphatesynthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2);Dihydroorotase (EC 3.5.2.3)]. 2Show
195RRADRAD_HUMANGTP-binding protein RAD (RAS associated with diabetes) (RAD1). 2Show
196RAF1RAF1_HUMANRAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf-1) (C-RAF) (cRaf). 8Show
197RAP1ARAP1A_HUMANRas-related protein Rap-1A precursor (GTP-binding protein smg-p21A)(Ras-related protein Krev-1) (C21KG) (G-22K). 2Show
198RAP1BRAP1B_HUMANRas-related protein Rap-1b precursor (GTP-binding protein smg p21B). 3Show
199RELREL_HUMANC-Rel proto-oncogene protein (C-Rel protein). 1Show
200RASGRF1RGRF1_HUMANRas-specific guanine nucleotide-releasing factor 1 (Ras-GRF1) (Guaninenucleotide-releasing protein) (Ras-specific nucleotide exchange factorCDC25) (Guanine nucleotide-releasing factor 1). 1Show
201RGS10RGS10_HUMANRegulator of G-protein signaling 10 (RGS10). 2Show
202RGS14RGS14_HUMANRegulator of G-protein signaling 14 (RGS14). 4Show
203RHOARHOA_HUMANTransforming protein RhoA precursor (H12). 2Show
204GRK1RK_HUMANRhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupledreceptor kinase 1). 1Show
205HNRNPA1ROA1_HUMANHeterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizingprotein) (Single-strand RNA-binding protein) (hnRNP core protein A1). 1Show
206RAP1GAPRPGP1_HUMANRap1 GTPase-activating protein 1 (Rap1GAP1) (Rap1GAP). 4Show
207RYR1RYR1_HUMANRyanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1)(RYR-1) (Skeletal muscle calcium release channel). 2Show
208RYR2RYR2_HUMANRyanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2)(RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel)(hRYR-2). 3Show
209SNAPAPS25BP_HUMANSNARE-associated protein Snapin (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein). 2Show
210SLC4A4S4A4_HUMANElectrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonatecotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4member 4) (kNBC1). 4Show
211SLC5A5SC5A5_HUMANSodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Sodium-iodidesymporter) (Na(+)/I(-)-symporter) (Solute carrier family 5 member 5). 1Show
212SCN7ASCN7A_HUMANSodium channel protein type 7 subunit alpha (Sodium channel proteintype VII subunit alpha) (Putative voltage-gated sodium channel subunitalpha Nax) (Sodium channel protein cardiac and skeletal muscle subunitalpha). 4Show
213SGK1SGK1_HUMANSerine/threonine-protein kinase Sgk1 (EC 2.7.11.1)(Serum/glucocorticoid-regulated kinase 1). 1Show
214AANATSNAT_HUMANSerotonin N-acetyltransferase (EC 2.3.1.87) (Aralkylamine N-acetyltransferase) (AA-NAT) (Serotonin acetylase). 4Show
215SNAP25SNP25_HUMANSynaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated25 kDa protein) (Super protein) (SUP). 1Show
216SOX9SOX9_HUMANTranscription factor SOX-9. 2Show
217SPTBN1SPTB2_HUMANSpectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1)(Beta-II spectrin) (Fodrin beta chain). 1Show
218SRCSRC_HUMANProto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src). 2Show
219SRFSRF_HUMANSerum response factor (SRF). 2Show
220SSTR5SSR5_HUMANSomatostatin receptor type 5 (SS5R). 1Show
221STARSTAR_HUMANSteroidogenic acute regulatory protein, mitochondrial precursor (StAR)(StARD1). 2Show
222STK11STK11_HUMANSerine/threonine-protein kinase 11 (EC 2.7.11.1) (Serine/threonine-protein kinase LKB1) (Renal carcinoma antigen NY-REN-19). 2Show
223STK24STK24_HUMANSerine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinaseMST3) (MST-3) (Mammalian STE20-like protein kinase 3). 2Show
224AURKASTK6_HUMANSerine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)(Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase). 2Show
225STMN1STMN1_HUMANStathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18)(Leukemia-associated phosphoprotein p18) (pp17) (Prosolin)(Metablastin) (Protein Pr22). 5Show
226STMN2STMN2_HUMANStathmin-2 (Protein SCG10) (Superior cervical ganglion-10 protein). 2Show
227STOMSTOM_HUMANErythrocyte band 7 integral membrane protein (Stomatin) (Protein7.2b). 2Show
228STXBP5STXB5_HUMANSyntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae proteinhomolog 3). 1Show
229SISUIS_HUMANSucrase-isomaltase, intestinal [Contains: Sucrase (EC 3.2.1.48);Isomaltase (EC 3.2.1.10)]. 2Show
230DARSSYDC_HUMANAspartyl-tRNA synthetase, cytoplasmic (EC 6.1.1.12) (Aspartate--tRNAligase) (AspRS) (Cell proliferation-inducing gene 40 protein). 1Show
231SYN1SYN1_HUMANSynapsin-1 (Synapsin I) (Brain protein 4.1). 2Show
232SYN2SYN2_HUMANSynapsin-2 (Synapsin II). 2Show
233TAL1TAL1_HUMANT-cell acute lymphocytic leukemia protein 1 (TAL-1) (Stem cellprotein) (T-cell leukemia/lymphoma protein 5). 1Show
234MAPTTAU_HUMANMicrotubule-associated protein tau (Neurofibrillary tangle protein)(Paired helical filament-tau) (PHF-tau). 14Show
235RELATF65_HUMANTranscription factor p65 (Nuclear factor NF-kappa-B p65 subunit). 1Show
236THOP1THOP1_HUMANThimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78). 2Show
237TNNI3TNNI3_HUMANTroponin I, cardiac muscle (Cardiac troponin I). 4Show
238NGFRTNR16_HUMANTumor necrosis factor receptor superfamily member 16 precursor (Low-affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR)(p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen). 2Show
239TPH1TPH1_HUMANTryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase1). 3Show
240TSC2TSC2_HUMANTuberin (Tuberous sclerosis 2 protein). 2Show
241ZFP36TTP_HUMANTristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36)(Protein TIS11A) (TIS11) (Growth factor-inducible nuclear proteinNUP475) (G0/G1 switch regulatory protein 24). 3Show
242THTY3H_HUMANTyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH). 8Show
243UHRF1UHRF1_HUMANE3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Ubiquitin-like PHD andRING finger domain-containing protein 1) (Ubiquitin-like-containingPHD and RING finger domains protein 1) (Inverted CCAAT box-bindingprotein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc fingerprotein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106). 1Show
244UNC84BUN84B_HUMANProtein unc-84 homolog B (Sad1/unc-84 protein-like 2) (Rab5-interacting protein) (Rab5IP). 3Show
245VASPVASP_HUMANVasodilator-stimulated phosphoprotein (VASP). 9Show
246VDRVDR_HUMANVitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclearreceptor subfamily 1 group I member 1). 1Show
247VIMVIME_HUMANVimentin. 13Show
248VTNVTNC_HUMANVitronectin precursor (Serum-spreading factor) (S-protein) (V75)[Contains: Vitronectin V65 subunit; Vitronectin V10 subunit;Somatomedin-B]. 3Show
249WT1WT1_HUMANWilms tumor protein (WT33). 4Show