|Group: AGC Family: PKC Subfamily: Alpha|
Description: protein kinase C, alpha
Gene Symbol: PRKCA
Synonyms: AAG6, MGC129900, MGC129901, PKC-alpha, PKCA, PRKACA
UniprotKB/SwissProt: KPCA_HUMAN (P17252)
Function: This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.