Regulatory Network in Protein Phosphorylation
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Kinase: PKN1 protein kinase N1

Group: AGC      Family: PKN      

Description: protein kinase N1

Gene Symbol: PKN1

Synonyms: DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1

UniprotKB/SwissProt: PKN1_HUMAN (Q16512)

Function: Can phosphorylate ribosomal protein S6. Mediates GTPase Rho dependent intracellular signaling (By similarity).

Subcellular Localization: Cytoplasm (By similarity).

Protein Domain:
PDB:1CXZ

The substrate proteins of kinase PKN1

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1MARCKSMARCS_HUMANMyristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinaseC substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein). 3Show
2CDC25CMPIP3_HUMANM-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificityphosphatase Cdc25C). 1Show
3PKN1PKN1_HUMANSerine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-likePKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha). 9Show
4MAPTTAU_HUMANMicrotubule-associated protein tau (Neurofibrillary tangle protein)(Paired helical filament-tau) (PHF-tau). 7Show



The substrate proteins of kinase family PKN

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1MARCKSMARCS_HUMANMyristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinaseC substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein). 3Show
2CDC25CMPIP3_HUMANM-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificityphosphatase Cdc25C). 1Show
3PKN1PKN1_HUMANSerine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-likePKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha). 9Show
4MAPTTAU_HUMANMicrotubule-associated protein tau (Neurofibrillary tangle protein)(Paired helical filament-tau) (PHF-tau). 7Show