Regulatory Network in Protein Phosphorylation
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Kinase: ChaK2 transient receptor potential cation channel, subfamily M, member 6

Group: Atypical      Family: Alpha      Subfamily: ChaK

Description: transient receptor potential cation channel, subfamily M, member 6

Gene Symbol: TRPM6

Synonyms: CHAK2, HMGX, HOMG, HSH

UniprotKB/SwissProt: TRPM6_HUMAN (Q9BX84)

Function: Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region.

Subcellular Localization: Membrane; Multi-pass membrane protein.

Protein Domain:

The substrate proteins of kinase family ChaK

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1ANXA1ANXA1_HUMANAnnexin A1 (Annexin-1) (Annexin I) (Lipocortin I) (Calpactin II)(Chromobindin-9) (p35) (Phospholipase A2 inhibitory protein). 2Show