Regulatory Network in Protein Phosphorylation
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Kinase: BCR breakpoint cluster region

Group: Atypical      Family: BCR      

Description: breakpoint cluster region

Gene Symbol: BCR

Synonyms: ALL, BCR/FGFR1, BCR1, CML, D22S11, D22S662, FGFR1/BCR, FLJ16453, PHL

UniprotKB/SwissProt: BCR_HUMAN (P11274)

Function: GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.

Subcellular Localization:

Protein Domain:
PDB:1K1F

The substrate proteins of kinase BCR

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1YWHAQ1433T_HUMAN14-3-3 protein theta (14-3-3 protein tau) (14-3-3 protein T-cell)(Protein HS1). 1Show
2MLLT4AFAD_HUMANAfadin (Protein AF-6). 1Show



The substrate proteins of kinase family BCR

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1YWHAQ1433T_HUMAN14-3-3 protein theta (14-3-3 protein tau) (14-3-3 protein T-cell)(Protein HS1). 1Show
2MLLT4AFAD_HUMANAfadin (Protein AF-6). 1Show