|Group: CAMK Family: CAMK2 |
Description: calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
Gene Symbol: CAMK2A
Synonyms: CAMKA, KIAA0968
UniprotKB/SwissProt: KCC2A_HUMAN (Q9UQM7)
Function: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).
Subcellular Localization: Cell junction, synapse, presynaptic cell membrane (By similarity). Cell junction, synapse (By similarity). Note=Postsynaptic lipid rafts (By similarity).