Regulatory Network in Protein Phosphorylation
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Kinase: MARK3 MAP/microtubule affinity-regulating kinase 3

Group: CAMK      Family: CAMKL      Subfamily: MARK

Description: MAP/microtubule affinity-regulating kinase 3

Gene Symbol: MARK3

Synonyms: CTAK1, KP78, PAR1A

UniprotKB/SwissProt: MARK3_HUMAN (P27448)

Function: Involved in the specific phosphorylation of microtubule- associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'.

Subcellular Localization:

Protein Domain:

The substrate proteins of kinase MARK3

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1KSR1KSR1_HUMANKinase suppressor of Ras 1. 1Show
2KSR2KSR2_HUMANKinase suppressor of Ras 2 (hKSR2). 1Show
3CDC25CMPIP3_HUMANM-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificityphosphatase Cdc25C). 1Show



The substrate proteins of kinase family MARK

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1KSR1KSR1_HUMANKinase suppressor of Ras 1. 1Show
2KSR2KSR2_HUMANKinase suppressor of Ras 2 (hKSR2). 1Show
3MAP2MAP2_HUMANMicrotubule-associated protein 2 (MAP 2) (MAP-2). 7Show
4MAP4MAP4_HUMANMicrotubule-associated protein 4 (MAP 4). 5Show
5CDC25CMPIP3_HUMANM-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificityphosphatase Cdc25C). 1Show
6MAPTTAU_HUMANMicrotubule-associated protein tau (Neurofibrillary tangle protein)(Paired helical filament-tau) (PHF-tau). 12Show