|Group: CAMK Family: CAMKL Subfamily: NuaK|
Description: NUAK family, SNF1-like kinase, 2
Gene Symbol: NUAK2
Synonyms: DKFZP434J037, DKFZp686F01113, FLJ90349, SNARK
UniprotKB/SwissProt: NUAK2_HUMAN (Q9H093)
Function: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95- activated tumor cells.