Regulatory Network in Protein Phosphorylation
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Kinase: QIK SNF1-like kinase 2

Group: CAMK      Family: CAMKL      Subfamily: QIK

Description: SNF1-like kinase 2

Gene Symbol: SNF1LK2

Synonyms: DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SIK2

UniprotKB/SwissProt: SN1L2_HUMAN (Q9H0K1)

Function: Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.

Subcellular Localization: Cytoplasm (By similarity).

Protein Domain:

The substrate proteins of kinase QIK

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1IRS1IRS1_HUMANInsulin receptor substrate 1 (IRS-1). 1Show



The substrate proteins of kinase family QIK

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1IRS1IRS1_HUMANInsulin receptor substrate 1 (IRS-1). 1Show