|Group: CAMK Family: CAMKL Subfamily: QIK|
Description: SNF1-like kinase
Gene Symbol: SNF1LK
Synonyms: MSK, SIK
UniprotKB/SwissProt: SN1L1_HUMAN (P57059)
Function: Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3 (By similarity).
Subcellular Localization: Cytoplasm. Nucleus. Note=Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ.