|Group: CAMK Family: MAPKAPK Subfamily: MNK|
Description: MAP kinase interacting serine/threonine kinase 1
Gene Symbol: MKNK1
UniprotKB/SwissProt: MKNK1_HUMAN (Q9BUB5)
Function: May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Subcellular Localization: Isoform 2: Cytoplasm. Isoform 3: Cytoplasm. Nucleus.