Regulatory Network in Protein Phosphorylation
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Kinase: skMLCK myosin light chain kinase 2, skeletal muscle

Group: CAMK      Family: MLCK      

Description: myosin light chain kinase 2, skeletal muscle

Gene Symbol: MYLK2

Synonyms: KMLC, MLCK, skMLCK

UniprotKB/SwissProt: MYLK2_HUMAN (Q9H1R3)

Function: Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain.

Subcellular Localization: Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.

Protein Domain:

The substrate proteins of kinase family MLCK

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1MRLC2MLRM_HUMANMyosin regulatory light chain 2, nonsarcomeric (Myosin RLC). 1Show
2MYL9MLRN_HUMANMyosin regulatory light chain 2, smooth muscle isoform (Myosin RLC)(Myosin regulatory light chain 9) (LC20). 2Show