Regulatory Network in Protein Phosphorylation
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Kinase: PKD1 protein kinase D1

Group: CAMK      Family: PKD      

Description: protein kinase D1

Gene Symbol: PRKD1

Synonyms: PKC-MU, PKCM, PKD, PRKCM

UniprotKB/SwissProt: KPCD1_HUMAN (Q15139)

Function: This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.

Subcellular Localization:

Protein Domain:

The substrate proteins of kinase PKD1

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1HDAC5HDAC5_HUMANHistone deacetylase 5 (HD5) (Antigen NY-CO-9). 3Show
2HDAC7AHDAC7_HUMANHistone deacetylase 7a (HD7a). 3Show
3HSPB1HSPB1_HUMANHeat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)(Stress-responsive protein 27) (SRP27) (Estrogen-regulated 24 kDaprotein) (28 kDa heat shock protein). 1Show
4PRKD1KPCD1_HUMANSerine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Proteinkinase D) (Protein kinase C mu type) (nPKC-mu). 6Show
5PLCG1PLCG1_HUMAN1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1(EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1)(Phospholipase C-gamma-1) (PLC-II) (PLC-148). 1Show
6PPP1R14APP14A_HUMANProtein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiatedinhibitory protein of PP1) (CPI-17). 2Show
7RIN1RIN1_HUMANRas and Rab interactor 1 (Ras interaction/interference protein 1) (Rasinhibitor JC99). 1Show



The substrate proteins of kinase family PKD

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1ARMSARMS_HUMANAnkyrin repeat-rich membrane spanning protein (Kinase D-interactingsubstrate of 220 kDa). 1Show
2COL4A3BPC43BP_HUMANCollagen type IV alpha-3-binding protein (Ceramide transfer protein)(hCERT) (Goodpasture antigen-binding protein) (GPBP) (StAR-relatedlipid transfer protein 11) (StARD11) (START domain-containing protein11). 1Show
3GSK3AGSK3A_HUMANGlycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha). 1Show
4HDAC5HDAC5_HUMANHistone deacetylase 5 (HD5) (Antigen NY-CO-9). 3Show
5HDAC7AHDAC7_HUMANHistone deacetylase 7a (HD7a). 3Show
6HSPB1HSPB1_HUMANHeat shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27)(Stress-responsive protein 27) (SRP27) (Estrogen-regulated 24 kDaprotein) (28 kDa heat shock protein). 1Show
7PRKD1KPCD1_HUMANSerine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Proteinkinase D) (Protein kinase C mu type) (nPKC-mu). 6Show
8PRKD2KPCD2_HUMANSerine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2). 2Show
9PLCG1PLCG1_HUMAN1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1(EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1)(Phospholipase C-gamma-1) (PLC-II) (PLC-148). 1Show
10PPP1R14APP14A_HUMANProtein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiatedinhibitory protein of PP1) (CPI-17). 2Show
11RIN1RIN1_HUMANRas and Rab interactor 1 (Ras interaction/interference protein 1) (Rasinhibitor JC99). 2Show