|Group: CK1 Family: VRK |
Description: vaccinia related kinase 1
Gene Symbol: VRK1
Synonyms: MGC117401, MGC138280, MGC142070
UniprotKB/SwissProt: VRK1_HUMAN (Q99986)
Function: Serine/threonine kinase that phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2.
Subcellular Localization: Nucleus. Note=Dispersed throughout the cell but not located on mitotic spindle or chromatids during mitosis.