Regulatory Network in Protein Phosphorylation
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Kinase: PITSLRE cell division cycle 2-like 2 (PITSLRE proteins)

Group: CMGC      Family: CDK      Subfamily: PITSLRE

Description: cell division cycle 2-like 2 (PITSLRE proteins)

Gene Symbol: CDC2L2

Synonyms: CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, MGC131975, PITSLRE, p58GTA

UniprotKB/SwissProt: CD2L2_HUMAN (Q9UQ88)

Function: Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.

Subcellular Localization: Cytoplasm. Nucleus.

Protein Domain: