|Group: CMGC Family: CDK Subfamily: PITSLRE|
Description: cell division cycle 2-like 2 (PITSLRE proteins)
Gene Symbol: CDC2L2
Synonyms: CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, MGC131975, PITSLRE, p58GTA
UniprotKB/SwissProt: CD2L2_HUMAN (Q9UQ88)
Function: Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.
Subcellular Localization: Cytoplasm. Nucleus.