Regulatory Network in Protein Phosphorylation
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Kinase: CLK1 CDC-like kinase 1

Group: CMGC      Family: CLK      

Description: CDC-like kinase 1

Gene Symbol: CLK1

Synonyms: CLK, CLK/STY, STY

UniprotKB/SwissProt: CLK1_HUMAN (P49759)

Function: Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines (By similarity).

Subcellular Localization: Nucleus.

Protein Domain:
PDB:1Z57

The substrate proteins of kinase CLK1

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1PTPN1PTN1_HUMANTyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48)(Protein-tyrosine phosphatase 1B) (PTP-1B). 4Show



The substrate proteins of kinase family CLK

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1PTPN1PTN1_HUMANTyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48)(Protein-tyrosine phosphatase 1B) (PTP-1B). 7Show