Regulatory Network in Protein Phosphorylation
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Kinase: CLK3 CDC-like kinase 3

Group: CMGC      Family: CLK      

Description: CDC-like kinase 3

Gene Symbol: CLK3

Synonyms: FLJ22858

UniprotKB/SwissProt: CLK3_HUMAN (P49761)

Function: Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines.

Subcellular Localization: Nucleus. Cytoplasm (By similarity). Acrosome (By similarity).

Protein Domain:
PDB:2EU9

The substrate proteins of kinase family CLK

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1PTPN1PTN1_HUMANTyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48)(Protein-tyrosine phosphatase 1B) (PTP-1B). 7Show