|Group: CMGC Family: CLK |
Description: CDC-like kinase 4
Gene Symbol: CLK4
UniprotKB/SwissProt: CLK4_HUMAN (Q9HAZ1)
Function: Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines. Required for the regulation of alternative splicing of MAPT/TAU.
Subcellular Localization: Nucleus (By similarity).