Regulatory Network in Protein Phosphorylation
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Kinase: CLK4 CDC-like kinase 4

Group: CMGC      Family: CLK      

Description: CDC-like kinase 4

Gene Symbol: CLK4

Synonyms: DKFZp686A20267

UniprotKB/SwissProt: CLK4_HUMAN (Q9HAZ1)

Function: Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines. Required for the regulation of alternative splicing of MAPT/TAU.

Subcellular Localization: Nucleus (By similarity).

Protein Domain:

The substrate proteins of kinase family CLK

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1PTPN1PTN1_HUMANTyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48)(Protein-tyrosine phosphatase 1B) (PTP-1B). 7Show