|Group: CMGC Family: DYRK Subfamily: DYRK2|
Description: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Gene Symbol: DYRK3
Synonyms: DYRK5, RED, REDK
UniprotKB/SwissProt: DYRK3_HUMAN (O43781)
Function: Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
Subcellular Localization: Nucleus.