Regulatory Network in Protein Phosphorylation
[Home] [About] [Browse Kinome] [Phosphorylation Prediction] [Expression Analysis] [Statistics] [Help] Version 1.0

[Back to Kinome Table]
Kinase: HIPK3 homeodomain interacting protein kinase 3

Group: CMGC      Family: DYRK      Subfamily: HIPK

Description: homeodomain interacting protein kinase 3

Gene Symbol: HIPK3

Synonyms: DYRK6, FIST3, PKY, YAK1

UniprotKB/SwissProt: HIPK3_HUMAN (Q9H422)

Function: Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors.

Subcellular Localization: Cytoplasm. Nucleus.

Protein Domain:

The substrate proteins of kinase HIPK3

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1FADDFADD_HUMANProtein FADD (FAS-associated death domain protein) (FAS-associatingdeath domain-containing protein) (Mediator of receptor inducedtoxicity). 2Show



The substrate proteins of kinase family HIPK

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1CTBP1CTBP1_HUMANC-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1). 1Show
2FADDFADD_HUMANProtein FADD (FAS-associated death domain protein) (FAS-associatingdeath domain-containing protein) (Mediator of receptor inducedtoxicity). 2Show
3TP53P53_HUMANCellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53)(Antigen NY-CO-13). 3Show