Regulatory Network in Protein Phosphorylation
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Kinase: Erk3(MAPK6) mitogen-activated protein kinase 6

Group: CMGC      Family: MAPK      Subfamily: ERK3

Description: mitogen-activated protein kinase 6

Gene Symbol: MAPK6

Synonyms: DKFZp686F03189, ERK3, HsT17250, PRKM6, p97MAPK

UniprotKB/SwissProt: MK06_HUMAN (Q16659)

Function: Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle (By similarity).

Subcellular Localization:

Protein Domain:
PDB:2I6L

The substrate proteins of kinase Erk3(MAPK6)

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1IER3IEX1_HUMANRadiation-inducible immediate-early gene IEX-1 (Immediate earlyprotein GLY96) (Immediate early response 3 protein) (PACAP-responsivegene 1 protein) (Protein PRG1) (Differentiation-dependent gene 2protein) (Protein DIF-2). 1Show
2MAPK6MK06_HUMANMitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellularsignal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK). 2Show



The substrate proteins of kinase family ERK3

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1IER3IEX1_HUMANRadiation-inducible immediate-early gene IEX-1 (Immediate earlyprotein GLY96) (Immediate early response 3 protein) (PACAP-responsivegene 1 protein) (Protein PRG1) (Differentiation-dependent gene 2protein) (Protein DIF-2). 1Show
2MAPK6MK06_HUMANMitogen-activated protein kinase 6 (EC 2.7.11.24) (Extracellularsignal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK). 2Show