Regulatory Network in Protein Phosphorylation
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Kinase: Erk1(MAPK3) mitogen-activated protein kinase 3

Group: CMGC      Family: MAPK      Subfamily: ERK1

Description: mitogen-activated protein kinase 3

Gene Symbol: MAPK3

Synonyms: ERK1, HS44KDAP, HUMKER1A, MGC20180, P44ERK1, P44MAPK, PRKM3

UniprotKB/SwissProt: MK03_HUMAN (P27361)

Function: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4).

Subcellular Localization:

Protein Domain:

The substrate proteins of kinase Erk1(MAPK3)

No.Gene NameUniProtKB ID