Regulatory Network in Protein Phosphorylation
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Kinase: p38b(MAPK11) mitogen-activated protein kinase 11

Group: CMGC      Family: MAPK      Subfamily: p38

Description: mitogen-activated protein kinase 11

Gene Symbol: MAPK11

Synonyms: P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta

UniprotKB/SwissProt: MK11_HUMAN (Q15759)

Function: Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Phosphorylates preferentially transcription factor ATF2.

Subcellular Localization:

Protein Domain:

The substrate proteins of kinase p38b(MAPK11)

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1EEF2KEF2K_HUMANElongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K)(Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase). 1Show
2HBP1HBP1_HUMANHMG box-containing protein 1 (HMG box transcription factor 1) (Highmobility group box transcription factor 1). 1Show
3HNF4AHNF4A_HUMANHepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factorHNF-4) (Nuclear receptor subfamily 2 group A member 1) (Transcriptionfactor 14). 1Show
4MAPKAPK5MAPK5_HUMANMAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activatedprotein kinase 5) (MAPKAP kinase 5) (p38-regulated/activated proteinkinase). 2Show
5ZNHIT1ZNHI1_HUMANZinc finger HIT domain-containing protein 1 (Cyclin-G1-binding protein1) (Zinc finger protein subfamily 4A member 1) (p18 Hamlet). 1Show



The substrate proteins of kinase family p38

No.Gene NameUniProtKB IDProtein DescriptionNu