Regulatory Network in Protein Phosphorylation
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Kinase: SRPK2 SFRS protein kinase 2

Group: CMGC      Family: SRPK      

Description: SFRS protein kinase 2

Gene Symbol: SRPK2

Synonyms: FLJ36101, SFRSK2

UniprotKB/SwissProt: SRPK2_HUMAN (P78362)

Function: Phosphorylates RS domain-containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.

Subcellular Localization: Cytoplasm. Nucleus.

Protein Domain: