|Group: Other Family: BUB |
Description: BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast)
Gene Symbol: BUB1
Synonyms: BUB1A, BUB1L, hBUB1
UniprotKB/SwissProt: BUB1_HUMAN (O43683)
Function: Involved in cell cycle checkpoint enforcement. Can interact and phosphorylate BUB3.
Subcellular Localization: Nucleus (By similarity). Kinetochore (By similarity). Note=Nuclear in interphase cells. Kinetochore localization is required for normal mitotic timing and checkpoint response to spindle damage (By similarity).