|Group: Other Family: CAMKK Subfamily: Meta|
Description: calcium/calmodulin-dependent protein kinase kinase 1, alpha
Gene Symbol: CAMKK1
Synonyms: CAMKKA, DKFZp761M0423, MGC34095
UniprotKB/SwissProt: KKCC1_HUMAN (Q8N5S9)
Function: Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.
Subcellular Localization: Cytoplasm (By similarity). Nucleus (By similarity).