|Group: Other Family: CAMKK Subfamily: Meta|
Description: calcium/calmodulin-dependent protein kinase kinase 2, beta
Gene Symbol: CAMKK2
Synonyms: CAMKK, CAMKKB, KIAA0787, MGC15254
UniprotKB/SwissProt: KKCC2_HUMAN (Q96RR4)
Function: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin- binding domain are inactive. Seems to be involved in hippocampal activation of CREB1 (By similarity).
Subcellular Localization: Cytoplasm (By similarity).