|Group: CMGC Family: CK2 |
Description: casein kinase 2, alpha 1 polypeptide
Gene Symbol: CSNK2A1
Synonyms: CK2A1, CKII, CKII alpha
UniprotKB/SwissProt: CSK21_HUMAN (P68400)
Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.