Function: Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3 (By similarity).
Subcellular Localization: Cytoplasm.
The substrate proteins of kinase IKKb
Number of kinase-specific phosphorylation sites
Forkhead box protein O3 (Forkhead in rhabdomyosarcoma-like 1) (AF6q21protein).