Regulatory Network in Protein Phosphorylation
[Home] [About] [Browse Kinome] [Phosphorylation Prediction] [Expression Analysis] [Statistics] [Help] Version 1.0

[Back to Kinome Table]
Kinase: NEK9 NIMA (never in mitosis gene a)- related kinase 9

Group: Other      Family: NEK      Subfamily: NEK8

Description: NIMA (never in mitosis gene a)- related kinase 9

Gene Symbol: NEK9

Synonyms: DKFZp434D0935, MGC138306, MGC16714, NERCC, NERCC1, Nek8

UniprotKB/SwissProt: NEK9_HUMAN (Q8TD19)

Function: Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.

Subcellular Localization: Cytoplasm. Nucleus.

Protein Domain:

The substrate proteins of kinase NEK9

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1NEK6NEK6_HUMANSerine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-relatedprotein kinase 6) (Protein kinase SID6-1512). 2Show
2NEK7NEK7_HUMANSerine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-relatedprotein kinase 7). 2Show
3NEK9NEK9_HUMANSerine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-relatedprotein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1kinase) (NIMA-related kinase 8) (Nek8). 1Show



The substrate proteins of kinase family NEK8

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1NEK8NEK8_HUMANSerine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosisA-related kinase 8) (NimA-related protein kinase 8) (NIMA-relatedkinase 12a). 1Show