Regulatory Network in Protein Phosphorylation
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Kinase: NRBP1 nuclear receptor binding protein 1

Group: Other      Family: NRBP      

Description: nuclear receptor binding protein 1

Gene Symbol: NRBP1

Synonyms: BCON3, FLJ27109, FLJ35541, MADM, MUDPNP, NRBP

UniprotKB/SwissProt: NRBP_HUMAN (Q9UHY1)

Function: May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.

Subcellular Localization: Cytoplasm, cell cortex. Intracytoplasmic membrane. Cell projection, lamellipodium. Note=Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.

Protein Domain: