|Group: Other Family: NRBP |
Description: nuclear receptor binding protein 1
Gene Symbol: NRBP1
Synonyms: BCON3, FLJ27109, FLJ35541, MADM, MUDPNP, NRBP
UniprotKB/SwissProt: NRBP_HUMAN (Q9UHY1)
Function: May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.
Subcellular Localization: Cytoplasm, cell cortex. Intracytoplasmic membrane. Cell projection, lamellipodium. Note=Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.