|Group: Other Family: PEK Subfamily: HRI|
Description: eukaryotic translation initiation factor 2-alpha kinase 1
Gene Symbol: EIF2AK1
Synonyms: HRI, KIAA1369
UniprotKB/SwissProt: E2AK1_HUMAN (Q9BQI3)
Function: Mediates down-regulation of protein synthesis in response to various stress conditions by the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser-51'. Protein synthesis is inhibited at the level of initiation (By similarity).