Regulatory Network in Protein Phosphorylation
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Kinase: PLK3 polo-like kinase 3 (Drosophila)

Group: Other      Family: PLK      Subfamily: PLK2

Description: polo-like kinase 3 (Drosophila)

Gene Symbol: PLK3

Synonyms: CNK, FNK, PRK

UniprotKB/SwissProt: PLK3_HUMAN (Q9H4B4)

Function: Serine/threonine protein kinase involved in regulating M phase functions during the cell cycle. May also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein.

Subcellular Localization: Membrane; Peripheral membrane protein.

Protein Domain:

The substrate proteins of kinase PLK3

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1CHEK2CHK2_HUMANSerine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1). 1Show
2CDC25CMPIP3_HUMANM-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificityphosphatase Cdc25C). 3Show
3TP53P53_HUMANCellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53)(Antigen NY-CO-13). 1Show