|Group: Other Family: SCY1 |
Description: SCY1-like 1 (S. cerevisiae)
Gene Symbol: SCYL1
Synonyms: GKLP, HT019, MGC78454, NKTL, NTKL, P105, TAPK, TEIF, TRAP
UniprotKB/SwissProt: NTKL_HUMAN (Q96KG9)
Function: Isoform 6 acts as transcriptional activator. Isoform 6 binds to three different type of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. Isoform 6 binds also to the TERT promoter region. Has no detectable kinase activity in vitro.
Subcellular Localization: Centrosome. Isoform 1: Cytoplasm. Note=Cytoplasmic throughout the cell cycle. Isoform 2: Cytoplasm. Note=Cytoplasmic throughout the cell cycle. Isoform 3: Cytoplasm. Centrosome. Note=Cytoplasmic during interphase and centrosomal during mitosis, it locali