|Group: Other Family: TLK |
Description: tousled-like kinase 2
Gene Symbol: TLK2
Synonyms: MGC44450, PKU-ALPHA
UniprotKB/SwissProt: TLK2_HUMAN (Q86UE8)
Function: Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.
Subcellular Localization: Nucleus.