Regulatory Network in Protein Phosphorylation
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Kinase: TLK2 tousled-like kinase 2

Group: Other      Family: TLK      

Description: tousled-like kinase 2

Gene Symbol: TLK2

Synonyms: MGC44450, PKU-ALPHA

UniprotKB/SwissProt: TLK2_HUMAN (Q86UE8)

Function: Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.

Subcellular Localization: Nucleus.

Protein Domain: