|Group: STE Family: STE-Unique |
Description: mitogen-activated protein kinase kinase kinase 14
Gene Symbol: MAP3K14
Synonyms: FTDCR1B, HS, HSNIK, NIK
UniprotKB/SwissProt: M3K14_HUMAN (Q99558)
Function: Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Induces the processing of NF-kappa-B 2/P100. Could act in a receptor-selective manner (By similarity).
Subcellular Localization: Cytoplasm.