Regulatory Network in Protein Phosphorylation
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Kinase: MAP3K3 mitogen-activated protein kinase kinase kinase 3

Group: STE      Family: STE11      Subfamily: MEKK2

Description: mitogen-activated protein kinase kinase kinase 3

Gene Symbol: MAP3K3

Synonyms: MAPKKK3, MEKK3

UniprotKB/SwissProt: M3K3_HUMAN (Q99759)

Function: Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.

Subcellular Localization:

Protein Domain:
PDB:2C60

The substrate proteins of kinase MAP3K3

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1MAP3K3M3K3_HUMANMitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25)(MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3). 1Show