Regulatory Network in Protein Phosphorylation
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Kinase: OSR1 oxidative-stress responsive 1

Group: STE      Family: STE20      Subfamily: FRAY

Description: oxidative-stress responsive 1

Gene Symbol: OXSR1

Synonyms: KIAA1101, OSR1

UniprotKB/SwissProt: OXSR1_HUMAN (O95747)

Function: Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.

Subcellular Localization:

Protein Domain:
PDB:2V3S

The substrate proteins of kinase OSR1

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1PAK1PAK1_HUMANSerine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activatedkinase 1) (PAK-1) (p65-PAK) (Alpha-PAK). 2Show
2SLC12A2S12A2_HUMANSolute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter). 3Show