|Group: STE Family: STE20 Subfamily: KHS|
Description: mitogen-activated protein kinase kinase kinase kinase 2
Gene Symbol: MAP4K2
Synonyms: BL44, GCK, RAB8IP
UniprotKB/SwissProt: M4K2_HUMAN (Q12851)
Function: Enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. May play a role in the regulation of vesicle targeting or fusion.
Subcellular Localization: Cytoplasm (By similarity). Basolateral cell membrane; Peripheral membrane protein (By similarity). Golgi apparatus membrane; Peripheral membrane protein (By similarity).