|Group: STE Family: STE20 Subfamily: STLK|
Description: amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2
Gene Symbol: ALS2CR2
Synonyms: CALS-21, ILPIP, ILPIPA, MGC102916, PAPK, PRO1038
UniprotKB/SwissProt: AL2S2_HUMAN (Q9C0K7)
Function: Pseudokinase which, in complex with CAB39, binds to and activates STK11. Relocates STK11 from the nucleus to the cytoplasm. Plays an essential role in STK11-mediated G1 cell cycle arrest.
Subcellular Localization: Nucleus. Cytoplasm.