|Group: STE Family: STE7 Subfamily: MEK5|
Description: mitogen-activated protein kinase kinase 5
Gene Symbol: MAP2K5
Synonyms: HsT17454, MAPKK5, MEK5, PRKMK5
UniprotKB/SwissProt: MP2K5_HUMAN (Q13163)
Function: Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.