Regulatory Network in Protein Phosphorylation
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Kinase: TNK1 tyrosine kinase, non-receptor, 1

Group: TK      Family: Ack      

Description: tyrosine kinase, non-receptor, 1

Gene Symbol: TNK1

Synonyms: MGC46193

UniprotKB/SwissProt: TNK1_HUMAN (Q13470)

Function: Involved in negative regulation of cell growth. May have tumor suppressor properties. May play a negative regulatory role in the Ras-MAPK pathway (By similarity). May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.

Subcellular Localization: Cytoplasm. Membrane; Peripheral membrane protein.

Protein Domain:

The substrate proteins of kinase family Ack

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1TNK2ACK1_HUMANActivated CDC42 kinase 1 (EC (ACK-1) (Tyrosine kinase non-receptor protein 2). 1Show