|Group: TK Family: Ack |
Description: tyrosine kinase, non-receptor, 1
Gene Symbol: TNK1
UniprotKB/SwissProt: TNK1_HUMAN (Q13470)
Function: Involved in negative regulation of cell growth. May have tumor suppressor properties. May play a negative regulatory role in the Ras-MAPK pathway (By similarity). May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
Subcellular Localization: Cytoplasm. Membrane; Peripheral membrane protein.