|Group: TK Family: JakA |
Description: Janus kinase 3 (a protein tyrosine kinase, leukocyte)
Gene Symbol: JAK3
Synonyms: JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
UniprotKB/SwissProt: JAK3_HUMAN (P52333)
Function: Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and interleukin-4 signaling pathway. Phosphorylates STAT6, IRS1, IRS2 and PI3K.
Subcellular Localization: Intracytoplasmic membrane; Peripheral membrane protein (By similarity). Note=Wholly intracellular, possibly membrane associated (By similarity).