Regulatory Network in Protein Phosphorylation
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Kinase: MET met proto-oncogene (hepatocyte growth factor receptor)

Group: TK      Family: Met      

Description: met proto-oncogene (hepatocyte growth factor receptor)

Gene Symbol: MET

Synonyms: HGFR, RCCP2

UniprotKB/SwissProt: MET_HUMAN (P08581)

Function: Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity.

Subcellular Localization: Membrane; Single-pass type I membrane protein.

Protein Domain:
PDB:1FYR

The substrate proteins of kinase MET

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1GAB1GAB1_HUMANGRB2-associated-binding protein 1 (Growth factor receptor boundprotein 2-associated protein 1) (GRB2-associated binder 1). 18Show
2METMET_HUMANHepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGFreceptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor)(Met proto-oncogene tyrosine kinase) (c-Met). 5Show
3SPSB1SPSB1_HUMANSPRY domain-containing SOCS box protein 1 (SSB-1). 1Show



The substrate proteins of kinase family Met

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1GAB1GAB1_HUMANGRB2-associated-binding protein 1 (Growth factor receptor boundprotein 2-associated protein 1) (GRB2-associated binder 1). 18Show
2METMET_HUMANHepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGFreceptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor)(Met proto-oncogene tyrosine kinase) (c-Met). 5Show
3SPSB1SPSB1_HUMANSPRY domain-containing SOCS box protein 1 (SSB-1). 1Show