Regulatory Network in Protein Phosphorylation
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Kinase: RON macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

Group: TK      Family: Met      

Description: macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

Gene Symbol: MST1R

Synonyms: CDw136, PTK8, RON

UniprotKB/SwissProt: RON_HUMAN (Q04912)

Function: Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity.

Subcellular Localization: Membrane; Single-pass type I membrane protein.

Protein Domain:

The substrate proteins of kinase RON

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1MST1RRON_HUMANMacrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSPreceptor) (p185-Ron) (CD136 antigen) (CDw136) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulatingprotein receptor beta chain]. 8Show



The substrate proteins of kinase family Met

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1GAB1GAB1_HUMANGRB2-associated-binding protein 1 (Growth factor receptor boundprotein 2-associated protein 1) (GRB2-associated binder 1). 18Show
2METMET_HUMANHepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGFreceptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor)(Met proto-oncogene tyrosine kinase) (c-Met). 5Show
3SPSB1SPSB1_HUMANSPRY domain-containing SOCS box protein 1 (SSB-1). 1Show