Regulatory Network in Protein Phosphorylation
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Kinase: YES v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1

Group: TK      Family: Src      Subfamily: SrcA

Description: v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1

Gene Symbol: YES1

Synonyms: HsT441, P61-YES, Yes, c-yes

UniprotKB/SwissProt: YES_HUMAN (P07947)

Function: Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.

Subcellular Localization: Cytoplasm, cytosol. Note=In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.

Protein Domain:
PDB:2HDA

The substrate proteins of kinase YES

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1CBLCBL_HUMANE3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transductionprotein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto-oncogene) (RING finger protein 55). 2Show
2YES1YES_HUMANProto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c-Yes). 2Show