Regulatory Network in Protein Phosphorylation
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Kinase: BMX BMX non-receptor tyrosine kinase

Group: TK      Family: Tec      

Description: BMX non-receptor tyrosine kinase

Gene Symbol: BMX

Synonyms: ETK, PSCTK2, PSCTK3

UniprotKB/SwissProt: BMX_HUMAN (P51813)

Function: Activity is required for interleukin 6 (IL-6) induced differentiation. May play a role in the growth and differentiation of hematopoietic cells. May be involved in signal transduction in endocardial and arterial endothelial cells.

Subcellular Localization: Cytoplasm (Probable).

Protein Domain:
PDB:2EKX

The substrate proteins of kinase BMX

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1RUFY1RUFY1_HUMANRUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1)(Zinc finger FYVE domain-containing protein 12) (La-binding protein 1)(Rab4-interacting protein). 2Show



The substrate proteins of kinase family Tec

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1BMXBMX_HUMANCytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrowtyrosine kinase gene in chromosome X protein) (Epithelial andendothelial tyrosine kinase) (ETK) (NTK38). 3Show
2BTKBTK_HUMANTyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase)(Agammaglobulinaemia tyrosine kinase) (ATK) (B-cell progenitor kinase)(BPK). 1Show
3PTPN18PTN18_HUMANTyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48)(Brain-derived phosphatase). 3Show
4TECTEC_HUMANTyrosine-protein kinase Tec (EC 2.7.10.2). 2Show