|Group: TK Family: Trk |
Description: neurotrophic tyrosine kinase, receptor, type 3
Gene Symbol: NTRK3
Synonyms: TRKC, gp145(trkC)
UniprotKB/SwissProt: NTRK3_HUMAN (Q16288)
Function: Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties.
Subcellular Localization: Membrane; Single-pass type I membrane protein.